Antimicrobial metabolite profiling of Nigrospora sphaerica from Adiantum philippense L.
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چکیده
منابع مشابه
Metabolite Profiling of the Extracts of Endophytic Fungi of Entomopathogenic Significance, Aspergillus flavus and Nigrospora sphaerica Isolated from Tropical Tree Species of India, Tectona grandis L
India needs newer group of biopesticides. Biopesticides are part of the insecticide field, their market is increasing. Biopesticides are secondary metabolites include thousands of alkaloids, terpenoids, phenolics and minor secondary chemicals derived from plants, microbes, animals, and certain minerals. Several endophytic microbes are known to have anti-insect properties. Endophytes are microbe...
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This paper reports on the vinca alkaloid produced by a novel Nigrospora sphaerica isolated from Catharanthus roseus. Through liquid chromatography-mass spectrometry (LCMS), only the crude mycelia extract of this fungus was positive for determination of vinblastine. This vinca alkaloid was then purified by using high-performance liquid chromatography (HPLC) and tested for cytotoxicity activity u...
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BACKGROUND Adiantum philippense (AP) is a pteridophyte that shows antihyperglycemic activity in vivo diabetic model, but the mechanism of action is unknown. OBJECTIVE AP was found to play a pivotal role in minimizing the high blood glucose in alloxan-induced diabetic rats. Simultaneously, it was observed that it could maintain the normal lipid profile even in diabetic condition. To investigat...
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BACKGROUND The emergence of multidrug resistant (MDR) pathogens is of great concern to the global health community. Our ability to effectively treat diseases is based on the discovery of potent drugs for the treatment of these challenging diseases. Traditional medicines are one of the major sources for the discovery of safe, effective and economical drug candidates. In order to validate its ant...
متن کاملMetabolite profiling in Arabidopsis.
Metabolite profiling is the multiparallel relative quantification of a mixture of compounds or compound classes using chromatography and universal detection technologies (GC-MS, LC-MS). In this respect it is an extension of classical single-target methods from which it can be distinguished by its broader view on profiling major biochemical events. This broader scope of analysis outweighs the di...
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ژورنال
عنوان ژورنال: Journal of Genetic Engineering and Biotechnology
سال: 2020
ISSN: 2090-5920
DOI: 10.1186/s43141-020-00080-4